The World Health Organization (WHO) is celebrating the 25th anniversary of Research4Life, a program that has transformed access to scientific knowledge in more than 120 countries. Research4Life is a public-private partnership that provides researchers, educators, health professionals, and policymakers in low- and middle-income countries with free or affordable access to scientific journals, books, and databases. Over the past quarter-century, the initiative has helped millions of users gain the information they need to improve health, agriculture, and the environment. By bridging the knowledge gap, Research4Life has enabled local scientists and health workers to stay up-to-date with the latest research, which supports better decision-making and innovation. The program is made possible through collaboration between WHO, major publishers, and other partners. It covers multiple disciplines, including health, agriculture, and environmental sciences. Since its launch, Research4Life has expanded to include over 200 institutions and has provided access to more than 100,000 resources. The anniversary highlights the ongoing need for equitable access to knowledge, especially in underserved regions. WHO emphasizes that such initiatives are crucial for achieving global health goals and sustainable development.